Borsi Fehse

Graduated as Physician-biochemist from the Russian State Medical University (Moscow) in 1992 – German MD in theoretical medicine.

PhD (Dr. rer. nat.) at Heinrich-Pette-Institut for Experimental Virology and University of Hamburg in 1996.

Habilitation/Venia legendi in Molecular Medicine in 2002

W2/W3 professor for Experimental Paediatric Oncology and Haematology at Goethe University Frankfurt in 2007.

Since 2009 full (W3) professor for cell and gene therapy and Head of the respective Research Dept. at the Dept. of Stem Cell Transplantation, University Medical Centre Hamburg-Eppendorf (UKE) in Hamburg.

President e.o. (2018-2020) of the German Society of Gene Therapy

Since 2019: Speaker of the Working Group “Gene technology report” of the Berlin Brandenburg Academy of Sciences / since 2022: Berlin Institute of Health.

The main interest of BF is the permanent genetic modification of target cells for clinical gene therapy (e.g. adoptive immunotherapy, HIV gene therapy), but also basic and clinical research. He has long-standing experience with different types of retroviral vectors; his group has introduced the popular LeGO vector platform and innovative cell marking approaches such as RGB marking and optical barcoding. More recently, they have applied different genome-editing techniques (TALENs, CRISPR/Cas) for cell modification. Another major topic of his work has been the development of novel tools for molecular diagnostics in the context of stem cell transplantation and immunotherapy.